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Lupus is a disease that occurs when your body's immune system attacks your own tissues and organs (autoimmune disease) Inflammation caused by lupus can affect many different body systems — including your joints, skin, kidneys, blood cells, brain, heart and lungs Lupus can be difficult to diagnose because its signs and symptoms often mimic those of other ailments No hay dos casos de lupus exactamente iguales Los signos y síntomas pueden ser repentinos o desarrollarse lentamente, pueden ser leves o intensos, y temporales o permanentes La mayoría de las personas con lupus tiene una enfermedad leve que se caracteriza por tener episodios (denominados brotes) en los que los signos y síntomas empeoran durante un tiempo, después mejoran o incluso. Diagnosing lupus is difficult because signs and symptoms vary considerably from person to person Signs and symptoms of lupus may change over time and overlap with those of many other disorders No one test can diagnose lupus The combination of blood and urine tests, signs and symptoms, and physical examination findings leads to the diagnosis. Lupu r, colomer r, zugmaier g, sarup j, shepard m, slamon d, lippman me Direct interaction of a ligand for the erbb2 oncogene product with the egf receptor and p185erbb2. The findings were presented today by mayo clinic pathologist ruth lupu, ph.d., at the american association for cancer research (aacr) annual meeting 2012 One of the most devastating facts about pancreatic cancer is the paucity of effective drugs that exist to halt a tumor, dr At the age of 10, ruth lupu, ph.d., told her father she’d cure cancer “i probably didn’t know what cancer was,” laughs dr Lupu, a cancer researcher with mayo clinic’s center for biomedical discovery Lupu didn’t know cancer then, she certainly does now. Awards and honors 2002 outstanding achievement award 7th world congress on advances in oncology and international symposium on molecular medicine conference, crete, greece 2001 outstanding achievement award 6th world congress on advances in oncology and international symposium on molecular medicine conference, athens greece 1990 young investigators award abbott laboratories 1987 fogarti award. Lupus nephritis occurs when lupus autoantibodies affect parts of the kidneys that filter out waste This causes swelling and irritation of the kidneys, called inflammation It might lead to blood in the urine, protein in the urine, high blood pressure, kidneys that don't work well or even kidney failure. Besides the usual blood and urine tests, urine collected over 24 hours might be tested These tests measure how well the kidneys are working A small section of kidney tissue is removed and sent to a lab This test diagnoses lupus nephritis It also can help show how bad the disease is There can be more than one biopsy over time.