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Empty sella syndrome (ess) is a rare and treatable condition that happens when your pituitary gland becomes flattened Ess causes certain symptoms such as frequent headaches and hormone imbalances. Empty sella syndrome affects the pituitary gland but may not cause symptoms Learn more about the condition, including symptoms, diagnosis, and treatment. Call your healthcare provider if your symptoms get worse or you have new ones Key points about empty sella syndrome empty sella syndrome (ess) affects a bony structure in the skull called the sella turcica This is where the pituitary gland is located With ess, imaging tests show the area looks larger than normal. What causes empty sella syndrome The causes of primary empty sella syndrome are poorly understood, though it is thought to occur due to an anatomical defect that causes csf to leak into the sella turcica and flatten the pituitary gland, thereby causing deficiencies in one or more pituitary hormones (e.g Empty sella syndrome (ess) is a disorder that involves the sella turcica, a bony structure at the base of the brain that surrounds and protects the pituitary gland. Empty sella syndrome is a rare condition that affects the skull Learn about its symptoms and causes, as well as treatment options. Empty sella syndrome is a radiological finding where spinal fluid is found within the sella, the space created for the pituitary Empty sella syndrome is divided into two categories based on degree Explore empty sella syndrome, a rare neurological condition characterized by the emptying or partial filling of the sella turcica